The accurate diagnosis of gout frequently constitutes a challenge in clinical practice, as it bears a close resemblance to other rheumatologic conditions.An undelayed diagnosis and an early therapeutic intervention using uric acid lowering therapy (ULT) is of the utmost importance for preventing bone destruction, the main point of managing gout pat
Background: Periprosthetic joint infection (PJI) represents a devastating consequence of total joint arthroplasty (TJA) because of its high morbidity and its high impact on patient quality of life.The lack of standardized preventive and treatment strategies is a major challenge for arthroplasty surgeons.The purpose of this article was to explore th
Human brain development is a complex process that evolves from early childhood to young adulthood.Major advances in brain imaging are increasingly being used to characterize the developing brain.These advances have further helped to elucidate the dynamic maturational processes that lead to the emergence of complex cognitive abilities in both typica
Glioblastoma (GBM) is the most common malignant brain tumor in adults, and immunotherapies and genetic therapies for GBM have lycogel evolved dramatically over the past decade, but GBM therapy is still facing a dilemma due to the high recurrence rate.The inflammatory microenvironment is a general signature of tumors that accelerates epigenetic chan